SAR245408 is primarily used as a potent and selective inhibitor of phosphoinositide 3-kinase (PI3K) pathways, particularly targeting the PI3Kα and PI3Kβ isoforms. Its main application lies in cancer research, where it is utilized to study tumor growth inhibition in various cell lines, especially those with mutations in the PI3K signaling pathway. Due to its ability to suppress downstream signaling molecules such as AKT, SAR245408 helps in evaluating the therapeutic potential of PI3K inhibition in oncology. It has been employed in preclinical studies to assess antiproliferative effects and apoptosis induction in solid tumors and hematological malignancies. Additionally, SAR245408 serves as a pharmacological tool to dissect the role of PI3K in cellular processes such as metabolism, survival, and proliferation.