GSK-2126458

10mM in DMSO

Reagent Code: #190212
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CAS Number 1086062-66-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 505.50 g/mol
Formula C₂₅H₁₇F₂N₅O₃S
thermostat Physical Properties
Melting Point 187-189 °C
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used primarily in research settings as a potent inhibitor of PI3K (phosphoinositide 3-kinase) and mTOR (mammalian target of rapamycin) pathways. These pathways are involved in cell growth, survival, and proliferation, making this compound valuable in studying cancer cell signaling. It has been investigated for its antitumor activity in various preclinical models, particularly in cancers with dysregulated PI3K/mTOR signaling. Due to its ability to cross the blood-brain barrier in experimental models, it is also explored for central nervous system malignancies. Not approved for clinical use and strictly limited to laboratory research.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿4,840.00

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