TG100-115 is primarily used in research settings to study its effects on cellular processes, particularly those involving the PI3K signaling pathway. It is known to selectively inhibit the p110δ and p110γ isoforms of PI3K, making it a valuable tool for investigating inflammation and immune responses. Researchers utilize it to explore its potential in treating inflammatory diseases, such as rheumatoid arthritis, by modulating immune cell activity. Additionally, it has been studied in the context of cancer, where PI3K signaling plays a critical role in tumor growth and survival. Its application in preclinical models helps in understanding the therapeutic potential of PI3K inhibition in various diseases.