PI-3065 is primarily used in research and development within the field of biochemistry and pharmacology. It serves as a potent and selective inhibitor of phosphoinositide 3-kinase (PI3K), specifically targeting the delta isoform. This makes it a valuable tool in studying the PI3K signaling pathway, which plays a critical role in cell growth, survival, and metabolism. Researchers utilize PI-3065 to investigate its potential therapeutic applications in diseases where PI3K-delta is implicated, such as cancer, inflammatory disorders, and autoimmune conditions. Its ability to selectively inhibit PI3K-delta helps in understanding the pathway's role in immune cell function and tumor progression, aiding in the development of targeted therapies. Additionally, PI-3065 is employed in preclinical studies to evaluate its efficacy and safety profile in various experimental models.