IC-87114
98%
Reagent
Code: #100905
CAS Number
371242-69-2
blur_circular Chemical Specifications
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Molecular Information
Weight
397.43 g/mol
Formula
C₂₂H₁₉N₇O
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Storage & Handling
Storage
-20°C
description Product Description
IC-87114 is primarily used in research settings as a selective inhibitor of the delta isoform of phosphoinositide 3-kinase (PI3Kδ). It is widely utilized in studies aimed at understanding the role of PI3Kδ in immune cell signaling and function. Researchers employ this compound to investigate its effects on B-cell activation, proliferation, and survival, which are crucial in autoimmune diseases and certain cancers. Additionally, IC-87114 is used to explore its potential therapeutic applications in conditions like chronic lymphocytic leukemia (CLL) and inflammatory disorders, where PI3Kδ signaling plays a significant role. Its specificity makes it a valuable tool for dissecting the contributions of PI3Kδ in cellular processes and disease mechanisms.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | White to grey solid |
| Purity (%) | 97.5-100 |
| NMR | Consistent With Structure |
| Infrared Spectrum | Conforms To Structure |
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