GNE-493 is primarily utilized in the field of biomedical research, particularly in the study of cancer biology. It functions as a potent and selective inhibitor of the PI3Kα pathway, which is often dysregulated in various cancers. Researchers use GNE-493 to investigate the role of PI3Kα signaling in tumor growth, survival, and resistance to therapies. Its application helps in understanding the molecular mechanisms of cancer progression and in the development of targeted therapeutic strategies. Additionally, GNE-493 is employed in preclinical studies to evaluate its efficacy and safety as a potential anticancer agent, providing insights for future drug development.