Morusin is a prenylated flavonoid widely studied for its potential therapeutic applications in medicine and health. It exhibits strong anti-cancer properties by inhibiting the growth of various cancer cells, including breast, lung, and liver cancers, through mechanisms such as inducing apoptosis and suppressing tumor proliferation. It also shows anti-inflammatory effects by inhibiting pro-inflammatory mediators like cytokines and prostaglandins, making it a candidate for treating inflammatory diseases like arthritis. Morusin possesses antioxidant properties that reduce oxidative stress and protect cells from damage. Additionally, it has antimicrobial activity against certain bacteria and viruses, suggesting potential in combating infections. Research explores its role in managing metabolic disorders, such as diabetes, via glucose level regulation and alpha-glucosidase inhibition. Further studies indicate benefits for skin health, including reducing hyperpigmentation, freckles, and dark spots by inhibiting tyrosinase activity, as well as immunomodulatory effects that balance the immune system. Overall, Morusin holds promise as a multi-functional compound in pharmaceutical, nutraceutical, and cosmeceutical applications.