Tussilagone is primarily studied for its anti-inflammatory and anti-asthmatic properties. It has shown potential in suppressing airway inflammation by inhibiting the release of pro-inflammatory cytokines and mediators such as TNF-α, IL-6, and NO. This makes it a candidate for development in respiratory conditions like asthma and chronic obstructive pulmonary disease (COPD). It also exhibits antioxidant activity, helping to reduce oxidative stress in cells, which may contribute to its protective effects in lung tissue. Research suggests tussilagone can modulate signaling pathways such as NF-κB and MAPK, which are involved in inflammation and immune responses. In traditional medicine contexts, it has been linked to cough suppression and relief of bronchial symptoms, supporting its use in herbal formulations for respiratory health. Ongoing studies are exploring its potential in neuroprotection and cancer prevention due to its bioactive properties, though these applications remain in early experimental stages.