Saikosaponin D is widely studied for its anti-inflammatory and immunomodulatory effects. It has shown potential in suppressing pro-inflammatory cytokines, making it relevant in research on autoimmune diseases and chronic inflammation. It also exhibits hepatoprotective properties, supporting liver health and function, and is investigated for use in liver disorders such as hepatitis and fibrosis. In cancer research, Saikosaponin D demonstrates anti-tumor activity by inducing apoptosis and inhibiting proliferation in various cancer cell lines, including liver, lung, and breast cancer. It may also enhance the efficacy of conventional chemotherapy agents. Additionally, it has neuroprotective effects and is explored for its role in managing neurodegenerative conditions like Alzheimer’s disease due to its ability to reduce oxidative stress and neuronal damage. Its antiviral activity, particularly against hepatitis B and C viruses, further broadens its therapeutic potential. Due to these diverse biological activities, Saikosaponin D is a key compound in traditional medicine formulations and a focus of modern drug development efforts.