Swertiamarine is widely used in traditional and modern medicine due to its significant hepatoprotective properties. It helps protect the liver from damage caused by toxins and supports liver function restoration, making it valuable in treating liver disorders such as hepatitis and fatty liver disease. It also exhibits anti-inflammatory and antioxidant activities, which contribute to its effectiveness in reducing inflammation and combating oxidative stress in various tissues.

In addition, swertiamarine has shown antidiabetic potential by helping regulate blood glucose levels. It enhances insulin secretion and improves insulin sensitivity, offering benefits in the management of type 2 diabetes. Its neuroprotective effects are being studied for possible use in neurodegenerative conditions like Alzheimer’s disease, where it may help reduce neuronal damage.

Swertiamarine is also used in herbal formulations for digestive disorders due to its bitter tonic properties, which stimulate appetite and improve digestion. Ongoing research explores its anticancer potential, as preliminary studies indicate it may inhibit the growth of certain cancer cells through apoptosis induction.