Periplocin is primarily used in traditional medicine for its cardiotonic properties, supporting heart function by enhancing myocardial contractility. It has been studied for potential anti-cancer effects, showing activity against certain tumor cell lines by inducing apoptosis and inhibiting cell proliferation. Research also suggests periplocin may have anti-inflammatory and immunomodulatory effects, making it of interest for developing treatments for chronic inflammatory conditions. Additionally, it has been explored for its neuroprotective potential in neurodegenerative diseases due to its ability to modulate signaling pathways involved in neuronal survival. However, its use is limited by narrow therapeutic window and potential toxicity, requiring careful dosage control in any medicinal application.