Norisoboldine is primarily studied for its anti-inflammatory and immunomodulatory effects. It has shown potential in the treatment of autoimmune and inflammatory diseases, particularly rheumatoid arthritis. The compound works by inhibiting key signaling pathways such as NF-κB and MAPK, which are involved in the production of pro-inflammatory cytokines. It also suppresses the activation and migration of immune cells, reducing joint inflammation and tissue damage in animal models. Due to these properties, norisoboldine is considered a promising candidate for developing natural product-based therapies for chronic inflammatory conditions. Additionally, it may contribute to gut health by modulating intestinal immune responses, suggesting possible applications in inflammatory bowel diseases.