Licochalcone A is widely used in skincare and cosmetic formulations due to its strong anti-inflammatory and antioxidant properties. It helps reduce redness and soothes irritated skin, making it beneficial in products targeting acne, rosacea, and sensitive skin. Its ability to inhibit melanin production also makes it effective in skin-lightening and brightening creams, helping to fade hyperpigmentation and even out skin tone. Additionally, Licochalcone A exhibits antimicrobial activity, which supports its use in anti-acne treatments by targeting acne-causing bacteria. In pharmaceutical research, it is studied for its potential anticancer effects, particularly in inhibiting the growth of certain tumor cells. Its natural origin and multifunctional activity make it a valuable ingredient in both dermatological and therapeutic applications.