Lanatoside C
10mM in DMSO
Reagent
Code: #201849
CAS Number
17575-22-3
science Other reagents with same CAS 17575-22-3
blur_circular Chemical Specifications
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Molecular Information
Weight
985.12 g/mol
Formula
C₄₉H₇₆O₂₀
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Registry Numbers
EC Number
41-546-1
MDL Number
MFCD00869432
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Physical Properties
Melting Point
272-274 °C
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Storage & Handling
Storage
-20°C
description Product Description
Lanatoside C is primarily used in the pharmaceutical industry for the treatment of heart-related conditions, particularly congestive heart failure and certain cardiac arrhythmias. It functions by inhibiting the Na⁺/K⁺-ATPase pump in cardiac muscle cells, which leads to increased intracellular sodium and calcium levels. This mechanism enhances myocardial contractility, resulting in improved cardiac output.
It is also used to control ventricular rate in patients with atrial fibrillation due to its effects on cardiac conduction, particularly by increasing vagal tone and slowing AV node conduction.
Due to its narrow therapeutic index, Lanatoside C requires careful dosing and monitoring. It is typically administered in hospital or clinical settings where cardiac function can be closely observed. Its use has declined somewhat with the advent of newer cardiac medications, but it remains an option in specific acute or refractory cases.
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