Integerrimine is primarily known for its presence in certain plants of the Boraginaceae family and has been studied for its biological activity. It exhibits hepatotoxic properties, which has led to interest in understanding its role in liver injury caused by herbal remedies containing pyrrolizidine alkaloids. Due to its toxicity, integerrimine is not used commercially in pharmaceuticals or industrial applications. However, it serves as a reference compound in toxicological studies, helping researchers assess the safety and purity of herbal products. Its detection in plant extracts is crucial for quality control in herbal medicine production to prevent contamination that could lead to human or animal poisoning.