Imperialine is primarily used in traditional medicine for its antitussive and expectorant properties, helping to relieve cough and facilitate the removal of mucus from the respiratory tract. It has shown potential in suppressing cough reflexes induced by irritants, making it valuable in formulations for respiratory conditions such as bronchitis and chronic obstructive pulmonary disease (COPD). Additionally, imperialine exhibits anti-inflammatory and mild sedative effects, which may contribute to its therapeutic action in calming airway irritation. Research also suggests possible antispasmodic activity, supporting its use in reducing bronchial spasms. Due to these combined effects, it is often included in herbal preparations aimed at managing respiratory discomfort and improving lung function.