Homoharringtonine
Analytical standard, 98%
Reagent
Code: #193665
Alias
High-santhine
CAS Number
26833-87-4
science Other reagents with same CAS 26833-87-4
blur_circular Chemical Specifications
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Molecular Information
Weight
545.62 g/mol
Formula
C₂₉H₃₉NO₉
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Registry Numbers
MDL Number
MFCD03410264
thermostat
Physical Properties
Melting Point
144-146 C
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Storage & Handling
Storage
2~8°C
description Product Description
Used in the treatment of chronic myeloid leukemia (CML), particularly in patients who are resistant to standard therapies. It works by inhibiting protein synthesis in cancer cells, leading to cell cycle arrest and apoptosis. Its application has been explored in clinical settings for acute myeloid leukemia (AML) and other myeloproliferative disorders. Due to its mechanism of action, it shows potential in targeting leukemic stem cells, which are often responsible for relapse. Clinical use is limited by toxicity and availability, but it remains an option in specialized treatment protocols.
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