Harpagide is primarily used in traditional and modern herbal medicine for its anti-inflammatory and analgesic properties. It is commonly employed to support the treatment of joint and musculoskeletal disorders, such as osteoarthritis and rheumatoid arthritis, by helping reduce pain and inflammation. The compound also exhibits hepatoprotective effects, making it useful in supporting liver health and protecting against liver damage induced by toxins. Additionally, harpagide has shown potential in modulating immune responses, which contributes to its use in managing chronic inflammatory conditions. It is sometimes included in dietary supplements aimed at promoting joint mobility and overall anti-aging wellness. Research also suggests neuroprotective benefits, indicating possible applications in supporting cognitive health and managing neurodegenerative diseases.