Homoharringtonine
10mM in DMSO
Reagent
Code: #193403
CAS Number
26833-87-4
science Other reagents with same CAS 26833-87-4
blur_circular Chemical Specifications
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Molecular Information
Weight
545.62 g/mol
Formula
C₂₉H₃₉NO₉
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Registry Numbers
MDL Number
MFCD03410264
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Storage & Handling
Storage
-20°C
description Product Description
Used in the treatment of chronic myeloid leukemia (CML), particularly in patients resistant to other therapies. It works by inhibiting protein synthesis in cancer cells, leading to cell cycle arrest and apoptosis. Clinical studies support its effectiveness in inducing remission in both chronic and accelerated phases of CML. Also under investigation for use in acute myeloid leukemia (AML) and other hematologic malignancies due to its potent anti-leukemic activity. Administered intravenously under medical supervision due to its narrow therapeutic index and potential toxicity.
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