Harpagide is primarily used in traditional and modern herbal medicine for its anti-inflammatory and analgesic properties. It is commonly employed to support the treatment of joint pain, arthritis, and lower back pain due to its ability to inhibit inflammatory pathways. The compound also exhibits hepatoprotective effects, making it useful in supporting liver health and protecting against toxin-induced liver damage. Additionally, harpagide has shown potential in modulating immune responses, which contributes to its use in managing autoimmune and chronic inflammatory conditions. It is often included in herbal formulations derived from *Harpagophytum procumbens* (devil's claw) for musculoskeletal support. Some studies suggest neuroprotective benefits, indicating possible applications in neurodegenerative disorders, though further research is needed in this area.