Guaiazulene is widely used in cosmetic and dermatological formulations due to its anti-inflammatory and antioxidant properties. It is commonly added to skincare products, especially those designed for sensitive, irritated, or post-procedure skin, as it helps reduce redness and soothe inflammation. Its deep blue color also serves as a natural dye in some products, providing an aesthetic appeal while delivering therapeutic benefits. Guaiazulene is frequently found in creams, lotions, serums, and after-sun products. It is also used in oral care products such as mouthwashes and toothpastes for its soothing and antiseptic effects. Additionally, it has been explored in topical treatments for minor skin irritations, burns, and radiation-induced dermatitis due to its ability to support skin healing.