Fisetin is a natural flavonoid found in many fruits and vegetables, known for its antioxidant properties. It is studied for its potential role in supporting brain health and cognitive function. Research suggests fisetin may help protect nerve cells from damage and support memory, making it a compound of interest in neurodegenerative conditions like Alzheimer’s disease. It also shows anti-inflammatory effects, which may help reduce chronic inflammation linked to aging and diseases such as arthritis and diabetes. Fisetin has been investigated for its ability to promote the clearance of damaged cells, a process known as senolysis, positioning it as a candidate in anti-aging research. Additionally, fisetin may support metabolic health by improving insulin signaling and glucose uptake. Some studies explore its role in cancer prevention due to its ability to influence cell cycle regulation and induce apoptosis in abnormal cells. While promising, most evidence comes from preclinical models, and human studies are still limited.