Fraxin is widely used in pharmaceutical and cosmetic industries due to its antioxidant and anti-inflammatory properties. It is incorporated into formulations aimed at skin protection and anti-aging, helping to reduce oxidative stress caused by environmental factors. In research, fraxin serves as a biomarker for monitoring certain metabolic processes and liver function, as it is a metabolite of esculetin. Its ability to modulate enzyme activity makes it valuable in studies related to diabetes and hepatoprotective agents. Additionally, fraxin is used in analytical chemistry as a reference standard for identifying coumarin derivatives in plant extracts.