Cnicin is a sesquiterpene lactone primarily extracted from blessed thistle (Cnicus benedictus). It is used in agricultural applications as a natural herbicide and plant growth inhibitor, controlling weed growth by suppressing seed germination and root development in competing plants, supporting sustainable and organic farming. Its allelopathic properties make it a candidate for eco-friendly bioherbicides. Additionally, cnicin exhibits pest management potential by deterring certain insect herbivores, reducing crop damage without synthetic chemicals. In medicinal contexts, it shows anti-inflammatory effects, stimulates digestive function, and supports liver detoxification and biliary health, often incorporated into herbal supplements. Ongoing research explores its anticancer properties, particularly in inhibiting growth of certain cancer cell types, positioning it as a bioactive compound for pharmaceutical development.