d-Bicuculline

Analytical reference substance, ≥99% (HPLC)

Reagent Code: #143183
label
Alias Dextrophic biquorine;(+)-Baiduinine, Biquorine, Dextrophic biquorine, Biquorine, Biquorine, Shantulin
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CAS Number 485-49-4

science Other reagents with same CAS 485-49-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 367.35 g/mol
Formula C₂₀H₁₇NO₆
badge Registry Numbers
EC Number 207-619-7
MDL Number MFCD00005006
thermostat Physical Properties
Melting Point 193-197 °C
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used primarily in neuroscience research to study the function of GABA_A receptors. Acts as a competitive antagonist at GABA_A receptors, blocking the inhibitory effects of GABA, the main inhibitory neurotransmitter in the central nervous system. This blockade leads to increased neuronal excitability, making it a valuable tool for inducing seizures in experimental models to study epilepsy. Also used to investigate synaptic transmission, neural circuitry, and the role of inhibitory signaling in behavior and brain function. Due to its potent convulsant properties, it is not used therapeutically but remains important in laboratory settings for probing the mechanisms of inhibition and excitation in the brain.

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Size Availability Unit Price Quantity
inventory 20mg
10-20 days ฿3,600.00

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d-Bicuculline
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Used primarily in neuroscience research to study the function of GABA_A receptors. Acts as a competitive antagonist at GABA_A receptors, blocking the inhibitory effects of GABA, the main inhibitory neurotransmitter in the central nervous system. This blockade leads to increased neuronal excitability, making it a valuable tool for inducing seizures in experimental models to study epilepsy. Also used to investigate synaptic transmission, neural circuitry, and the role of inhibitory signaling in behavior and brain function. Due to its potent convulsant properties, it is not used therapeutically but remains important in laboratory settings for probing the mechanisms of inhibition and excitation in the brain.
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