Paeonolide is primarily utilized in the field of traditional medicine and modern pharmacology due to its bioactive properties. It is often studied for its potential anti-inflammatory and analgesic effects, making it a candidate for developing treatments for conditions like arthritis and other inflammatory disorders. Additionally, paeonolide has shown promise in neuroprotective research, where it is explored for its ability to mitigate damage in neurological diseases. Its antioxidant properties are also being investigated for potential applications in skincare products aimed at reducing oxidative stress and aging. Furthermore, ongoing research is examining its role in cancer therapy, particularly in inhibiting the proliferation of certain cancer cells.