Liquiritin is widely used in the cosmetics industry due to its skin-lightening properties. It inhibits tyrosinase activity, which helps reduce melanin production, making it effective in treating hyperpigmentation and achieving an even skin tone. Additionally, it is incorporated into skincare products for its anti-inflammatory and antioxidant effects, which help soothe irritated skin and protect against environmental damage.

In traditional medicine, liquiritin is valued for its hepatoprotective properties, supporting liver health and aiding in detoxification processes. It is also used in formulations to alleviate symptoms of respiratory conditions, such as coughs and bronchitis, due to its expectorant and anti-inflammatory effects.

Furthermore, liquiritin is being studied for its potential neuroprotective benefits, showing promise in protecting against neurodegenerative diseases by reducing oxidative stress and inflammation in the brain. Its versatility makes it a valuable compound in both therapeutic and cosmetic applications.