Isoalantolactone is a natural sesquiterpene lactone found in plants of the Asteraceae family, such as Inula helenium. It is widely studied for its potential therapeutic applications in medicine and pharmaceuticals due to its diverse biological activities.

• Anticancer Activity: It inhibits the proliferation of various cancer cells, including breast, lung, liver, and colon cancers, by inducing apoptosis.
• Anti-inflammatory Properties: It reduces inflammation by inhibiting pro-inflammatory mediators like cytokines and prostaglandins, showing promise for treating conditions such as arthritis and chronic inflammatory diseases.
• Antimicrobial Effects: It demonstrates efficacy against certain bacteria and fungi, with potential for developing anti-infective agents.
• Hepatoprotective and Antioxidant Effects: It protects the liver from toxin-induced damage and oxidative stress by enhancing antioxidant enzyme activity, and generally safeguards cells from oxidative damage.
• Additional Research: Ongoing studies explore its use in diabetes, neurological disorders, and other conditions through modulation of cellular functions.

Research continues to evaluate isoalantolactone for drug development and natural therapies.