Thalidomide-NH-C6-NH-Boc is a derivative of thalidomide, modified with a Boc-protected aminohexyl linker. This compound is primarily used in medicinal chemistry and drug development research. Its application lies in its potential as a versatile intermediate for synthesizing more complex molecules, particularly in the design of targeted therapies. The Boc group serves as a protective moiety, allowing for selective chemical reactions to be carried out on other parts of the molecule. This compound is often employed in the development of proteolysis-targeting chimeras (PROTACs), which are innovative therapeutic agents designed to degrade specific disease-causing proteins. Additionally, its thalidomide core enables binding to cereblon, a protein involved in the ubiquitin-proteasome system, making it valuable in cancer research and the treatment of conditions like multiple myeloma. Its structural features also make it useful in exploring immunomodulatory and anti-inflammatory properties in various experimental models.