2,5-Dioxopyrrolidin-1-yl 4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzoate
97%
Reagent
Code: #40895
CAS Number
87736-89-8
blur_circular Chemical Specifications
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Molecular Information
Weight
327.2155 g/mol
Formula
C₁₃H₈F₃N₃O₄
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Registry Numbers
MDL Number
MFCD01075064
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Physical Properties
Melting Point
92-93 °C
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Storage & Handling
Storage
2-8°C
description Product Description
This chemical is widely used in photoaffinity labeling, a technique employed in biochemical research to study protein-ligand interactions. Its diazirine group, when exposed to ultraviolet light, generates a reactive carbene intermediate that forms covalent bonds with nearby molecules, allowing researchers to identify and map binding sites on proteins. The trifluoromethyl group enhances its stability and reactivity, making it a valuable tool for probing complex biological systems. Additionally, it is utilized in proteomics and drug discovery to investigate molecular interactions and validate drug targets with high precision. Its application extends to the development of new therapeutic agents by providing insights into the binding mechanisms of potential drugs.
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