Used as a phosphorylating agent in organic synthesis, particularly in the preparation of phosphate esters and nucleotide analogs. Its tri(cyclohexylammonium) salt form enhances solubility in organic solvents, making it suitable for reactions under anhydrous conditions. Commonly applied in the synthesis of prodrugs and bioactive molecules where controlled phosphorylation is required. Also utilized in research settings for modifying carbohydrates and nucleosides due to its selective reactivity and stability at room temperature.