(2-Aminoethyl)triphenylphosphonium Bromide
97%
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Used as a mitochondrial-targeting agent in biochemical and cellular research due to its ability to penetrate lipid membranes and accumulate in mitochondria. It serves as a delivery vehicle for attaching bioactive molecules to mitochondria, enabling studies on mitochondrial function, oxidative stress, and apoptosis. Commonly employed in the development of antioxidants such as MitoQ, where it is conjugated to ubiquinone to enhance cellular uptake and mitochondrial localization. Also utilized in neuroscience research for protecting neuronal cells from mitochondrial dysfunction linked to neurodegenerative diseases. Its positive charge facilitates interaction with the negatively charged mitochondrial membrane, making it a valuable tool in targeted drug delivery and cellular imaging applications.
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