Diethyl [(Tetrahydropyran-2-yloxy)methyl]phosphonate
96%
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description Product Description
Used as a key reagent in organic synthesis, particularly in the Horner-Wadsworth-Emmons (HWE) olefination reaction, enabling the selective formation of carbon-carbon double bonds. Its phosphonate group stabilizes carbanions, facilitating the generation of alkenes from aldehydes with high stereocontrol. The tetrahydropyranyl (THP) moiety acts as a protecting group for alcohols, allowing for selective deprotection under mild acidic conditions, which makes this compound valuable in multi-step synthesis of complex molecules such as natural products and pharmaceuticals. Its dual functionality supports controlled reactivity and improved solubility in common organic solvents, enhancing its utility in synthetic pathways.
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