Diethyl (3-Bromopropyl)phosphonate
≥95.0%(GC)
blur_circular Chemical Specifications
description Product Description
Used as an intermediate in organic synthesis, particularly as a reagent in the Horner-Wadsworth-Emmons (HWE) reaction for the stereoselective formation of alkenes from carbonyl compounds such as aldehydes and ketones, introducing a functionalized bromoalkyl chain. It is also employed in the preparation of more complex phosphonate-based compounds that serve as analogs of phosphate esters in medicinal chemistry. This compound plays a key role in the development of biologically active molecules, including potential enzyme inhibitors and antiviral agents. Its bromoalkyl group allows for further functionalization through nucleophilic substitution, making it valuable in building complex molecular architectures. Additionally, it is used in the synthesis of ligands for catalysis and in the preparation of specialty polymers with tailored properties.
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