Diethyl ((2-bromo-4-methylphenyl)difluoromethyl)phosphonate

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Reagent Code: #167366
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CAS Number 863977-42-8

science Other reagents with same CAS 863977-42-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 357.13 g/mol
Formula C₁₂H₁₆BrF₂O₃P
thermostat Physical Properties
Boiling Point 373.2±42.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.412±0.06 g/cm3(Predicted)
Storage 2-8°C, sealed, dry, light-proof

description Product Description

Used as a key intermediate in the synthesis of fluorinated pharmaceuticals and agrochemicals due to its ability to introduce difluoromethylphosphonate groups into organic molecules. Its bromo and methyl substituents allow for further functionalization through cross-coupling reactions, making it valuable in medicinal chemistry for developing bioactive compounds. Commonly employed in the preparation of enzyme inhibitors and kinase-targeted agents, where the phosphonate moiety mimics phosphate esters in biological systems. Also utilized in the development of novel pesticides, leveraging the stability and reactivity of the difluoromethyl group to enhance metabolic resistance and target specificity.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿16,670.00
inventory 250mg
10-20 days ฿28,310.00
inventory 1g
10-20 days ฿79,300.00

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Diethyl ((2-bromo-4-methylphenyl)difluoromethyl)phosphonate
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Used as a key intermediate in the synthesis of fluorinated pharmaceuticals and agrochemicals due to its ability to introduce difluoromethylphosphonate groups into organic molecules. Its bromo and methyl substituents allow for further functionalization through cross-coupling reactions, making it valuable in medicinal chemistry for developing bioactive compounds. Commonly employed in the preparation of enzyme inhibitors and kinase-targeted agents, where the phosphonate moiety mimics phosphate esters in bio

Used as a key intermediate in the synthesis of fluorinated pharmaceuticals and agrochemicals due to its ability to introduce difluoromethylphosphonate groups into organic molecules. Its bromo and methyl substituents allow for further functionalization through cross-coupling reactions, making it valuable in medicinal chemistry for developing bioactive compounds. Commonly employed in the preparation of enzyme inhibitors and kinase-targeted agents, where the phosphonate moiety mimics phosphate esters in biological systems. Also utilized in the development of novel pesticides, leveraging the stability and reactivity of the difluoromethyl group to enhance metabolic resistance and target specificity.

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