Benzyl Dimethylphosphonoacetate
>97%
Reagent
Code: #144738
CAS Number
57443-18-2
blur_circular Chemical Specifications
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Molecular Information
Weight
258.21 g/mol
Formula
C₁₁H₁₅O₅P
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used as a key reagent in organic synthesis, particularly in Horner-Wadsworth-Emmons (HWE) olefination reactions to form α,β-unsaturated esters. Its phosphonate group enables the construction of carbon-carbon double bonds with high selectivity and yield. Commonly employed in the synthesis of complex molecules such as pharmaceuticals, agrochemicals, and natural products. The benzyl group acts as a protecting group for the carboxylic ester, which can be easily removed via hydrogenolysis when needed. Its stability and reactivity make it valuable in multi-step synthetic routes.
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