Diethyl (1-oxo-1-phenylpropan-2-yl)phosphonate
96%
science Other reagents with same CAS 10409-56-0
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description Product Description
Used as a key intermediate in the synthesis of α,β-unsaturated carbonyl compounds through the Horner-Wadsworth-Emmons (HWE) olefination reaction. It enables the selective formation of trans-configured enones when reacted with aldehydes under basic conditions. Its phosphonate group stabilizes the carbanion, facilitating carbon-carbon bond formation in pharmaceutical and fine chemical manufacturing. Particularly valuable in constructing conjugated systems found in bioactive molecules and natural product analogs. Shows good reactivity with aromatic and aliphatic aldehydes, making it versatile in organic synthesis.
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