Dimethyl (1-Diazo-2-oxopropyl)phosphonate solution

10% in Acetonitrile

Reagent Code: #128588
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CAS Number 90965-06-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 192.11 g/mol
Formula C₅H₉N₂O₄P
badge Registry Numbers
MDL Number MFCD07368360
inventory_2 Storage & Handling
Storage 2-8°C, Inert Gas

description Product Description

Used as a key reagent in organic synthesis, particularly in homologation reactions to convert aldehydes and ketones into terminal alkenes through the Horner-Wadsworth-Emmons olefination pathway. It enables the introduction of a vinyl group under mild conditions, making it valuable in the construction of complex molecules such as natural products and pharmaceuticals. Its diazo functionality allows for metal-catalyzed cyclopropanation and insertion reactions, useful in developing bioactive compounds. The phosphonate group enhances stability and selectivity, offering advantages over traditional diazo compounds in both safety and reactivity. Commonly employed in research settings for C–C bond formation and ring expansion strategies.

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Test Parameter Specification
Appearance Liquid
Concentration (%) 9.5-10.5
Solvent Acetonitrile

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Size Availability Unit Price Quantity
inventory 5g
10-20 days ฿2,600.00

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