Dimethyl (1-Diazo-2-oxopropyl)phosphonate solution
10% in Acetonitrile
Reagent
Code: #128588
CAS Number
90965-06-3
blur_circular Chemical Specifications
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Molecular Information
Weight
192.11 g/mol
Formula
C₅H₉N₂O₄P
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Registry Numbers
MDL Number
MFCD07368360
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Storage & Handling
Storage
2-8°C, Inert Gas
description Product Description
Used as a key reagent in organic synthesis, particularly in homologation reactions to convert aldehydes and ketones into terminal alkenes through the Horner-Wadsworth-Emmons olefination pathway. It enables the introduction of a vinyl group under mild conditions, making it valuable in the construction of complex molecules such as natural products and pharmaceuticals. Its diazo functionality allows for metal-catalyzed cyclopropanation and insertion reactions, useful in developing bioactive compounds. The phosphonate group enhances stability and selectivity, offering advantages over traditional diazo compounds in both safety and reactivity. Commonly employed in research settings for C–C bond formation and ring expansion strategies.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | Liquid |
| Concentration (%) | 9.5-10.5 |
| Solvent | Acetonitrile |
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