1',3'-bis[1,2-dioleoyl-sn-glycero-3-phospho]-sn-glycerol (sodium salt)
>99%
Reagent
Code: #144601
Alias
18:1 Cardiophthalic lipid; tetraoleoyl cardiophthalic lipid; 1,1′,2,2′-tetra-(9Z-octadecanoyl) cardiophthalic lipid (sodium salt); CL (1′-[18:1 (9Z)/18:1 (9Z)] ,3′-[18:1 (9Z)/18:1 (9Z)]);
CAS Number
115404-77-8
Properties
Soluble in chloroform and alcohol (warmed with water content 3-5%) at concentrations up to 10 mg/mL. Insoluble in water and acetone.
science Other reagents with same CAS 115404-77-8
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Molecular Information
Weight
1501.96 g/mol
Formula
C₈₁H₁₄₈O₁₇P₂Na₂
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Storage & Handling
Storage
Room temperature, dry, sealed
description Product Description
Used as a lipid-based excipient in drug delivery systems, particularly in the formulation of liposomes and lipid nanoparticles (LNPs). Its structure supports membrane fluidity and stability, making it ideal for encapsulating therapeutic agents such as mRNA, siRNA, and other nucleic acids. Commonly applied in gene therapy and vaccine development due to its biocompatibility and ability to fuse with cell membranes, enhancing intracellular delivery. Also utilized in research settings to study membrane dynamics and lipid-lipid interactions in model bilayers.
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