LY-311727 is primarily used in research settings to study its effects on phospholipase A2 (PLA2) enzymes, which play a significant role in inflammatory processes. It acts as a potent inhibitor of secretory PLA2, making it a valuable tool for investigating the enzyme's role in various inflammatory diseases, such as arthritis, atherosclerosis, and other conditions involving excessive inflammation. Researchers utilize LY-311727 to understand the mechanisms of PLA2 inhibition and to explore potential therapeutic applications for inflammatory disorders. Its application is largely confined to laboratory studies, where it helps in developing insights into the biochemical pathways associated with inflammation and cellular signaling.