AN-2728 is primarily used in the treatment of inflammatory skin conditions, particularly psoriasis. It functions as a phosphodiesterase 4 (PDE4) inhibitor, which helps reduce inflammation by modulating the immune response. This makes it effective in alleviating symptoms such as redness, scaling, and discomfort associated with psoriasis. The compound is often formulated into topical creams or ointments for direct application to affected areas, providing targeted relief with minimal systemic side effects. Its mechanism of action offers a promising therapeutic option for patients seeking alternatives to traditional treatments like corticosteroids.