PF-3716556

10mM in DMSO

Reagent Code: #223988
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CAS Number 928774-43-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 394.47 g/mol
Formula C₂₂H₂₆N₄O₃
badge Registry Numbers
MDL Number MFCD19690947
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used in research as a potent and selective inhibitor of phosphodiesterase 10A (PDE10A), making it a valuable tool compound for studying neurological and psychiatric disorders such as schizophrenia and Huntington’s disease. Its high selectivity allows scientists to investigate the role of PDE10A in signal transduction pathways within the brain, particularly in the striatum, which is involved in motor control and cognition. Due to its pharmacological profile, it has been utilized in preclinical studies to assess the therapeutic potential of PDE10A inhibition on dopamine and glutamate signaling. It demonstrates good brain penetration and has been employed in animal models to evaluate effects on behavior, locomotor activity, and cognitive function.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿7,200.00

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