PDE4B-IN-2 is primarily used in research settings to study the role of phosphodiesterase 4B (PDE4B) in various biological processes. It is employed as a selective inhibitor to investigate the enzyme's involvement in inflammatory and immune responses. Researchers utilize this compound to explore potential therapeutic applications for conditions like asthma, chronic obstructive pulmonary disease (COPD), and autoimmune disorders. Additionally, it serves as a tool in understanding the signaling pathways mediated by cyclic AMP (cAMP), which is crucial for cellular regulation. Its application extends to preclinical studies aimed at developing novel treatments for neurological disorders, such as depression and cognitive impairments, where PDE4B plays a significant role.