PDE12-IN-3 is primarily utilized in biochemical research to study the role of phosphodiesterase 12 (PDE12) in cellular processes. It serves as a potent and selective inhibitor of PDE12, enabling scientists to investigate the enzyme's function in mRNA decay and its potential implications in various diseases. This compound is particularly valuable in exploring the regulation of gene expression and the development of therapeutic strategies targeting RNA metabolism. Additionally, PDE12-IN-3 is used in drug discovery efforts to identify novel treatments for conditions linked to PDE12 dysregulation, such as neurodegenerative disorders and certain cancers. Its application extends to in vitro and in vivo studies, providing insights into the molecular mechanisms underlying PDE12 activity and its impact on cellular homeostasis.