CI-1044 is primarily used in the field of medicinal chemistry and pharmacology, where it serves as a potent and selective inhibitor of phosphodiesterase 4 (PDE4). This enzyme plays a critical role in regulating inflammatory responses and cellular signaling pathways. By inhibiting PDE4, CI-1044 helps to reduce inflammation and is therefore studied for its potential therapeutic applications in treating inflammatory diseases such as asthma, chronic obstructive pulmonary disease (COPD), and rheumatoid arthritis. Additionally, its ability to modulate cyclic AMP levels makes it a candidate for research in neurological disorders, including depression and cognitive impairments, where PDE4 activity is implicated. The compound is also utilized in preclinical studies to better understand the biochemical pathways involved in inflammation and immune response, aiding in the development of novel anti-inflammatory drugs.