Chloro(diisopropylamino)methoxyphosphine is primarily used in organic synthesis as a reagent for the preparation of phosphonates and phosphinates. It is particularly valuable in the synthesis of biologically active compounds, where it facilitates the introduction of phosphorus-containing functional groups. This chemical is also employed in the development of pharmaceuticals, agrochemicals, and materials science, where its reactivity with various organic substrates is leveraged to create complex molecules. Additionally, it serves as a key intermediate in the production of flame retardants and other specialty chemicals, contributing to advancements in safety and performance in industrial applications.