Dicyclohexylphosphine oxide is widely used as a ligand in coordination chemistry, where it facilitates the stabilization of metal complexes. Its application is particularly significant in catalysis, aiding in various organic transformations such as hydrogenation and cross-coupling reactions. The compound is also employed in the synthesis of organophosphorus compounds, contributing to the development of flame retardants and plasticizers. Additionally, it serves as an extractant in solvent extraction processes, particularly for the separation and purification of metal ions. Its role in material science includes the modification of polymers to enhance their thermal and mechanical properties.