(2-Amino-5-bromophenyl)dimethylphosphineoxide
98%
science Other reagents with same CAS 2287288-82-6
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description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in reactions involving palladium-catalyzed cross-coupling due to the presence of the bromine moiety. The dimethylphosphine oxide group acts as a directing group in C–H activation reactions, enabling selective functionalization of aromatic rings. It is also employed in the development of ligands for transition metal catalysts, enhancing reactivity and selectivity in asymmetric synthesis. Its amino and phosphine oxide functionalities allow for further derivatization, making it valuable in medicinal chemistry for building complex heterocyclic systems.
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