(2-Amino-5-bromophenyl)dimethylphosphineoxide
98%
Reagent
Code: #139263
CAS Number
2287288-82-6
blur_circular Chemical Specifications
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Molecular Information
Weight
2486 g/mol
Formula
C₈H₁₁BrNOP
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Storage & Handling
Storage
2-8°C, avoiding light
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in reactions involving palladium-catalyzed cross-coupling due to the presence of the bromine moiety. The dimethylphosphine oxide group acts as a directing group in C–H activation reactions, enabling selective functionalization of aromatic rings. It is also employed in the development of ligands for transition metal catalysts, enhancing reactivity and selectivity in asymmetric synthesis. Its amino and phosphine oxide functionalities allow for further derivatization, making it valuable in medicinal chemistry for building complex heterocyclic systems.
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