(5-Bromopyrimidin-2-yl)dimethylphosphine oxide
95%
Reagent
Code: #131208
CAS Number
2613382-99-1
blur_circular Chemical Specifications
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Molecular Information
Weight
235.02 g/mol
Formula
C₆H₈BrN₂OP
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Registry Numbers
MDL Number
MFCD33032421
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Physical Properties
Boiling Point
334.4±34.0 °C(Predicted)
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Storage & Handling
Density
1.59±0.1 g/cm3(Predicted)
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer therapy. Its structure allows for selective cross-coupling reactions, making it valuable in medicinal chemistry for building complex heterocyclic systems. Commonly employed in Suzuki-Miyaura and other palladium-catalyzed reactions to introduce pyrimidine motifs into drug candidates. Also utilized in agrochemical research for designing bioactive molecules with improved stability and binding affinity.
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