Tricyclohexylphosphine oxide is primarily used as a ligand in organometallic chemistry and catalysis. It is often employed in the stabilization of metal complexes, enhancing their reactivity and selectivity in various chemical reactions. This compound is particularly useful in homogeneous catalysis, where it facilitates processes such as hydrogenation, hydroformylation, and polymerization. Additionally, it finds application in the synthesis of fine chemicals and pharmaceuticals, where its ability to modify the electronic and steric properties of metal centers is highly valuable. It also plays a role in the separation and purification of rare earth metals. In some cases, it is also utilized in the development of advanced materials, including polymers and coatings, due to its thermal stability and compatibility with a range of substrates.